Ensembl ID | ENSG00000142208

Transcript ID | ENST00000554581

Gene position | 14:105235686-105262088

Cytoband | 14q32.33

NCBI | 207

HGNC Id | 391

Refseq ID | NM_005163

CCDS ID | CCDS9994

Uniprot ID | P31749

UCSC ID | uc001ypm.4

OMIM ID | 164730

CIViC ID | 2

OncoKB | AKT1

Pharos | AKT1

Gene Type | protein-coding gene

Protein family | Pleckstrin homology domain containing;AKT kinases

Pathway(KEGG) | AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Diabetic cardiomyopathy, Dopaminergic synapse, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, Glucagon signaling pathway, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Measles, Melanoma, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Protein kinases, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway,

Pathway(Signor) | Adipogenesis, P38 Signaling and Myogenesis, Parkinson,

Pathway(Rectome) | AKT phosphorylates targets in the cytosol, AKT phosphorylates targets in the nucleus, AKT-mediated inactivation of FOXO1A, Activation of BAD and translocation to mitochondria, Activation of BH3-only proteins, Adaptive Immune System, Apoptosis, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, CD28 dependent PI3K/Akt signaling, Cell Cycle, Cell Cycle, Mitotic, Cellular response to chemical stress, Cellular responses to mechanical stimuli, Cellular responses to stimuli, Cellular responses to stress, Co-inhibition by CTLA4, Co-stimulation by CD28, Constitutive Signaling by AKT1 E17K in Cancer, Cyclin A:Cdk2-associated events at S phase entry, Cyclin E associated events during G1/S transition, Cytokine Signaling in Immune system, Deactivation of the beta-catenin transactivating complex, Developmental Biology, Disease, Diseases of signal transduction by growth factor receptors and second messengers, Downregulation of ERBB2 signaling, Downregulation of ERBB2:ERBB3 signaling, ESR-mediated signaling, Estrogen-dependent nuclear events downstream of ESR-membrane signaling, Extra-nuclear estrogen signaling, FLT3 Signaling, FOXO-mediated transcription, G beta:gamma signalling through PI3Kgamma, G-protein beta:gamma signalling, G1/S Transition, GPCR downstream signalling, Gene expression (Transcription), Generic Transcription Pathway, Hemostasis, High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells, Immune System, Infectious disease, Integrin signaling, Interleukin-4 and Interleukin-13 signaling, Intracellular signaling by second messengers, Intrinsic Pathway for Apoptosis, KEAP1-NFE2L2 pathway, KSRP (KHSRP) binds and destabilizes mRNA, MTOR signalling, Mechanical load activates signaling by PIEZO1 and integrins in osteocytes, Membrane Trafficking, Metabolism, Metabolism of RNA, Metabolism of cofactors, Metabolism of nitric oxide: NOS3 activation and regulation, Metabolism of vitamins and cofactors, Mitochondrial unfolded protein response (UPRmt), Mitotic G1 phase and G1/S transition, Negative regulation of NOTCH4 signaling, Negative regulation of the PI3K/AKT network, PI3K/AKT Signaling in Cancer, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, PIP3 activates AKT signaling, PTEN Regulation, PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1, Platelet Aggregation (Plug Formation), Platelet activation, signaling and aggregation, Programmed Cell Death, RAB GEFs exchange GTP for GDP on RABs, RNA Polymerase II Transcription, RUNX2 regulates genes involved in cell migration, Rab regulation of trafficking, Regulation of PTEN stability and activity, Regulation of T cell activation by CD28 family, Regulation of TP53 Activity, Regulation of TP53 Activity through Acetylation, Regulation of TP53 Activity through Association with Co-factors, Regulation of TP53 Degradation, Regulation of TP53 Expression and Degradation, Regulation of beta-cell development, Regulation of gene expression in beta cells, Regulation of localization of FOXO transcription factors, Regulation of mRNA stability by proteins that bind AU-rich elements, Response of endothelial cells to shear stress, S Phase, SARS-CoV Infections, SARS-CoV-2 Infection, SARS-CoV-2 targets host intracellular signalling and regulatory pathways, SARS-CoV-2-host interactions, Signal Transduction, Signaling by ERBB2, Signaling by GPCR, Signaling by Interleukins, Signaling by NOTCH, Signaling by NOTCH4, Signaling by Non-Receptor Tyrosine Kinases, Signaling by Nuclear Receptors, Signaling by PTK6, Signaling by Receptor Tyrosine Kinases, Signaling by VEGF, Signaling by WNT, TCF dependent signaling in response to WNT, TP53 Regulates Metabolic Genes, Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, Transcriptional Regulation by TP53, Transcriptional regulation by RUNX2, Translocation of SLC2A4 (GLUT4) to the plasma membrane, VEGFA-VEGFR2 Pathway, VEGFR2 mediated vascular permeability, Vesicle-mediated transport, Viral Infection Pathways, eNOS activation,

Pathway(Uniprot) | /