CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses.

Mutations, conservation, receptors, cross-activity, experimental assays

Binding and neutralizing viruses, binding sites, affinity, neutralization activity

Resistance mutations, virological characteristics, in vitro activity

Vaccine, neutralizing antibody, convalescent plasma, in vitro activity

Interagted B-cell epitope and T-cell epitope prediction tools

2023.11.7
Added antibody entries from 5304 to 12613.
2023.11
Added 35 SARS-CoV-2 variants and virologic characteristics.
2023.10.24
Added epitope search for SARS-CoV-2 variants.
2023.05
Added 8024 B-cell epitopes and 677 T-cell
epitopes.
2023.03
Added 10 SARS-CoV-2 varaints and virologic characteristics.
2023.02
Added epitope experimental assays and antibody network tree diagram in detailed page.
2023.01
Provided data download files.
2022.11
Started database building. Added epitope and antibody data.

Validated B epitopes

Validated T epitopes

Antibodies

Antibody structures

Affinity Records

Neutralizing Records

Virological characteristics

Therapeutics Records

In vitro activity Records

Predicted T epitopes

Records with information extracted from literature and computational analysis
Last updated on Nov 7, 2023

Extensive epitope and antibody data, including more than 60 000 epitopes and 12 000 antibodies.

Identification of HCoVs cross-reactive epitopes, and mutation and conservation annotation for epitopes and antibody binding sites.

Over 69 000 experimental interaction data of antibody affinity and neutralizing activity.

Virological characterization and more than 10 000 in vitro activity data of SARS-CoV-2 variants.