CanDriS Webserver Task
CanDriS is a software which uses an empirical Bayesian procedure to calculate the posterior probability of a site to be cancer-driving for all sites in a gene. To use it, please upload a mutation annotation format (maf) file that contains the somatic point mutations that are to be investigated. The file should contain the following four tab-delimited columns in the given order (including a header):
By default, you can run CanDriS just based on your own data if you have a big enough cohort or a unique tumor type samples differ from TCGA. Alternatively, you can also choose to run CanDriS by merging your sample into TCGA MC3 PANCAN or a specific tumor type data.
In the web page, we only display the sites with a posterior posibility over 0.5 for convenient. The complete result can be downloaded from the "Download" button at the bottom of the page.
Runtime depends on server usage and the size of the data set. Enter your e-mail address to receive the results when they are ready. Alternatively, you can keep the browser window open and check back later. It won't take a long time.