Mutations – TRAIT: T-cell Receptor-Antigen InTeraction database

Mutations

Data of mutations is necessary for the fact that affinity and specificity brought by variants plays an important role in the engineered TCRs and vaccines design. In TRAIT, a total of 1,031 TCR/antigen mutants are displayed on the "mutations" page to analyze their specific recognition traits and benefit immunotherapies.
• 29 TCRs have been related to their mutations, and detailed information can be accessed by clicking on the TCR name.
• 25 pMHCs have been related to their mutations, and detailed information can be accessed by clicking on the peptide name.

Mutations of TCRs related to certain antigen

Mutations of antigens related to certain TCR