Mutations – TRAIT: T-cell Receptor-Antigen InTeraction database

Mutations

Data of mutations is necessary for the fact that modification of affinity and specificity brought by mutants plays an important role in the engineered TCRs and vaccines design. In TRAIT, total 711 mutants of TCRs/antigens were displayed on the ‘mutations’ page to dissect traits of their specific recognition and benefit immunotherapies.
• 22 pMHCs have been related to their mutants. Detailed information can be accessed by click the name of peptide.
• 24 TCRs have been related to their mutants. Detailed information can be accessed by click the name of TCR.

Mutations of TCRs related to certain antigen

Mutations of antigens related to certain TCR

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About TRAIT

TRAIT is a multi-dimension database of T cell receptor antigen interaction with the aim to provide a versatile landscape of T cell receptor recognition of antigens.

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Correspondence

College of Pharmaceutical Sciences,
Zhejiang University, China

College of Computer Science and Technology,
Zhejiang University, China

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