{"id":52,"date":"2019-06-13T02:36:21","date_gmt":"2019-06-13T02:36:21","guid":{"rendered":"https:\/\/pgx.zju.edu.cn\/deephlapan\/?page_id=52"},"modified":"2021-03-30T02:49:54","modified_gmt":"2021-03-30T02:49:54","slug":"home","status":"publish","type":"page","link":"https:\/\/pgx.zju.edu.cn\/deephlapan\/","title":{"rendered":"Home"},"content":{"rendered":"\n<p><p><strong><em>DeepHLApan is a deep learning approach used for predicting high-confidence neoantigens by considering both the presentation possibilities of mutant peptides and the potential immunogenicity of pMHC. The stand-alone software is available in <a href=\"https:\/\/github.com\/jiujiezz\/deephlapan\">github<\/a>.<\/em><\/strong><\/p>\n<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"453\" src=\"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-2-1024x453.png\" alt=\"\" class=\"wp-image-65\" srcset=\"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-2-1024x453.png 1024w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-2-300x133.png 300w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-2-768x340.png 768w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-2.png 1302w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption><strong>The architecture of DeepHLApan<\/strong><\/figcaption><\/figure><\/div>\n\n\n\n<figure class=\"wp-block-image left\"><img loading=\"lazy\" decoding=\"async\" width=\"1240\" height=\"1240\" src=\"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S2b\u5434\u9759\u6210.png\" alt=\"\" class=\"wp-image-69\" srcset=\"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S2b\u5434\u9759\u6210.png 1240w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S2b\u5434\u9759\u6210-150x150.png 150w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S2b\u5434\u9759\u6210-300x300.png 300w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S2b\u5434\u9759\u6210-768x768.png 768w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S2b\u5434\u9759\u6210-1024x1024.png 1024w\" sizes=\"(max-width: 1240px) 100vw, 1240px\" \/><figcaption><strong>437,077 HLA-pairs covering 81 HLA alleles were used for training the binding model.<\/strong><\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image left\"><img loading=\"lazy\" decoding=\"async\" width=\"1240\" height=\"1240\" src=\"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S3.png\" alt=\"\" class=\"wp-image-71\" srcset=\"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S3.png 1240w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S3-150x150.png 150w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S3-300x300.png 300w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S3-768x768.png 768w, https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-content\/uploads\/2019\/06\/Figure-S3-1024x1024.png 1024w\" sizes=\"(max-width: 1240px) 100vw, 1240px\" \/><figcaption><strong>32,785 HLA-peptide pairs with 7,212 of them being immunogenic were used for training immunogenicity model.<\/strong><\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>DeepHLApan is a deep learning approach used for predicting high-confidence neoantigens by considering both the presentation possibilities of mutant peptides&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-52","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/pages\/52"}],"collection":[{"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/comments?post=52"}],"version-history":[{"count":109,"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/pages\/52\/revisions"}],"predecessor-version":[{"id":269,"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/pages\/52\/revisions\/269"}],"wp:attachment":[{"href":"https:\/\/pgx.zju.edu.cn\/deephlapan\/wp-json\/wp\/v2\/media?parent=52"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}